Alimta Millions Recovered Nationwide

Alimta Chemotherapy for Mesothelioma

Alimta belongs to the class of chemotherapy drugs called folate antimetabolites. It mimics natural substances present in human cells. When these substances become part of the cell’s metabolism, the cells cannot divide as they would normally.

Drugs known as antimetabolites interfere with the cell’s metabolism at particular phases and they are more specifically classified according to the substances with which they interfere.

Alimta is an antifolate, which means it inhibits the cell’s metabolic functions that depend upon folate and that are necessary in order for the cell to reproduce itself. Alimta works to prevent three enzymes, thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyl transferase (GARFT), which are required for the development of two nucleotides known as purine and pyrimidine. Nucleotides are molecules that form the structural units of RNA and DNA. If purine and pyrimidine aren’t made, neither is RNA and DNA, and this stops the survival of existing cancer cells and the growth of new ones.

Specific Dose Requirements for Alimta Mesothelioma Chemotherapy

When Alimta is given for the treatment of malignant pleural mesothelioma, it is administered in a dose of 500 mg/m2, or 500 milligrams per square meter of body surface area (BSA). There are several different formulas to measure BSA, but the one that is most often used is Mosteller’s, published in The New England Journal of Medicine in 1987. However, in general practice, an adult’s BSA is considered to be 1.7 m2.

The drug is given in combination with cisplatin in the following method:

Day 1 of the 21-day mesothelioma chemotherapy cycle, 500mg/m2 of Alimta administered intravenously. Thirty minutes later, 75 mg/m2 of cisplatin administered intravenously.

Mesothelioma chemotherapy with Alimta Side Effects

Chemotherapy patients on a regimen of cisplatin and Alimta may experience the following side effects:

  • Fatigue
  • Nausea
  • Anorexia
  • Vomiting
  • Constipation
  • Low white and red blood cell count
  • Low platelet level
  • Anemia
  • Sore throat
  • Mouth or lip sores

Special Instructions for the Use of Alimta for Mesothelioma Patients

The drug’s manufacturer, Eli Lilly and Company, makes the following recommendations before beginning treatment:

  • Patients treated with ALIMTA must be instructed to take folic acid and vitamin B12 as a prophylactic (preventative) measure to reduce treatment-related hematologic (blood) and gastrointestinal toxicity
  • Patients should be adequately informed of the risk of low blood cell counts and instructed to immediately contact their physician should any sign of infection develop including fever. Patients should also contact their physician if bleeding or symptoms of anemia occur.
  • Patients should be instructed to contact their physician if persistent vomiting, diarrhea, or signs of dehydration appear.
  • Patients should be instructed to inform the physician if they are taking any concomitant prescription (a prescription taken at the same time) or over-the-counter medications including those for pain or inflammation such as non-steroidal anti-inflammatory drugs.

We Take Our Clients' Cases Personal

Helping Victims of Mesothelioma Is Why We Do What We Do
  • Your firm has made this stressful process easy and comfortable for me.

    “In this difficult time for me, everyone in your office has been helpful and supportive in ensuring that not only are our objectives with my case met but also that my personal needs are accommodated.”

    - Stephen
  • I couldn’t have done it without you.

    “My case was complex, but you untangled the details of my asbestos exposure so that they were clear in court.”

    - Sam
  • The professionals at Shrader & Associates did the work, hassle free, and ensured I was able to leave a legacy for my family.

    “I hesitated to file suit because I thought going to trial would be a hassle. The professionals at Shrader & Associates did the work, hassle-free, and ensured I was able to leave a legacy for my family ...”

    - Raymond
  • Your team stood by me throughout the entire process.

    “The future looks a bit brighter for my family now.”

    - Frank
  • Thanks to you, the grief of my loss would have been almost unbearable otherwise.

    “The wonderful things you have done for us, the things you have made possible for my family, the doors you have opened – I will always be grateful.”

    - Brian
/

Experience You Can Count On

Our Awards & Accolades

  • HTLA
  • NADC Top 1%
  • America's Top 100
  • American Association for Justice Leaders Forum
  • Million Dollar Advocates Forum
  • American Association for Justice
  • AV Peer Reviewed Rated
  • Top 40 Under 40
  • Super Lawyers Rising Stars
  • Super Lawyers
  • Mesopthelioma Applied Research Foundation
  • Illionois Trial Lawyers Assocation
  • MTLA
  • Texas Trial Lawyers Association
  • American Association for Justice Leaders Forum 2021

Choosing the Right Law Firm is an Important & Personal Decision

Why Shrader & Associates?
  • AWARD-WINNING

    Our skilled approach to the practice of law has resulted in top ratings & awards from renowned legal organizations.

  • RESPECTED

    Our attorneys have been invited into some of the most prestigious and recognized professional associations in the U.S.

  • RECOGNIZED

    We’ve been featured on local and national news programs for our legal knowledge and winning results.

  • PROVEN

    To date, we’ve secured countless million-dollar results for clients located throughout the country.

The Right Team 
Makes a Difference

Mesothelioma cases require technical knowledge and an understanding of complex laws. An attorney with experience trying these claims and substantial resources to leverage on your behalf is your best bet to having a strong case. We are nationally recognized for providing quality representation to mesothelioma patients and their families.