miRview Meso Test
The miRview® Meso Test, developed by Rosetta Genomics, can be used it to tell whether or not a patient has malignant pleural mesothelioma. It is extremely accurate because it measures microRNA in a tumor sample.
How Does MicroRNA Help Pathologists Diagnose Mesothelioma?
MicroRNA is a unique group of RNA genes that control gene expression during translation, which is the process during which the genetic information on an mRNA molecule is used to make proteins. MicroRNA is expressed differently in the various types of cancer. The microRNA is taken from a number of tissue and body fluid samples and is used to identify a microRNA signature that is specific to mesothelioma.
How is the Test Performed?
The tissue and body fluid samples used in the testing are formalin-fixed paraffin embedded. A sample that is formalin-fixed paraffin embedded is material that has been biopsied and then placed in paraffin wax to prevent it from decaying or degenerating so that it can be analyzed under a microscope.
It is extremely significant that the miRview Meso Test can use microRNA from formalin-fixed paraffin embedded samples. These samples do not require any refrigeration and can be maintained at room temperature and sent to the lab for evaluation by standard shipping.
After the microRNA is removed from the samples and evaluated, a set of tissue-specific microRNA biomarkers is used to differentiate mesothelioma from other types of cancer.
How are the Test Results Interpreted?
The test measures the level of three microRNA biomarkers. Two scores are calculated, which indicate the amount of the three specific microRNAs in the sample as measured by qualitative real-time PCR (qRT-PCR). Qualitative real-time polymerase chain reaction, or qRT-PCR, is a technique that is used to increase the intensity of and count how many there are of a specific DNA molecule.
The test scores are then compared to predefined normal values. When both scores are greater than zero, the test outcome is mesothelioma.
The test has been shown to be 100 percent specific for mesothelioma and 94 percent accuracy level for diagnosing all subtypes of the disease.
Your firm has made this stressful process easy and comfortable for me.- Stephen
I couldn’t have done it without you.- Sam
The professionals at Shrader & Associates did the work, hassle free, and ensured I was able to leave a legacy for my family.- Raymond
Your team stood by me throughout the entire process.- Frank
Thanks to you, the grief of my loss would have been almost unbearable otherwise.- Brian
Our skilled approach to the practice of law has resulted in top ratings & awards from renowned legal organizations.
Our attorneys have been invited into some of the most prestigious and recognized professional associations in the U.S.
We’ve been featured on local and national news programs for our legal knowledge and winning results.
To date, we’ve secured countless million-dollar results for clients located throughout the country.
Mesothelioma cases require technical knowledge and an understanding of complex laws. An attorney with experience trying these claims and substantial resources to leverage on your behalf is your best bet to having a strong case. We are nationally recognized for providing quality representation to mesothelioma patients and their families.